Dr Sudeep Gupta
Dr. Sudeep Gupta – Director ACTREC

Endometrial Cancer Chemotherapy

Martee Hensley
Dr. Martee L.Hensley MSKCC

Clinical Utility of Prospective Molecular Characterization in Advanced Endometrial Cancer.

Soumerai TE, Donoghue MTA, Bandlamudi C, Srinivasan P, Chang MT, Zamarin D, Cadoo KA, Grisham RN, O’Cearbhaill RE, Tew WP, Konner JA, Hensley ML, Makker V, Sabbatini P, Spriggs DR, Troso-Sandoval TA, Charen AS, Friedman C, Gorsky M, Schweber SJ, Middha S, Murali R, Chiang S, Park KJ, Soslow RA, Ladanyi M, Li BT, Mueller J, Weigelt B, Zehir A, Berger MF, Abu-Rustum NR, Aghajanian C, DeLair DF, Solit DB, Taylor BS, Hyman DM.

Clin Cancer Res. 2018 Dec 1;24(23):5939-5947. doi: 10.1158/1078-0432.CCR-18-0412. Epub 2018 Aug 1.PMID: 30068706 Free PMC Article

PC (paclitaxel and carboplatin, CarboTaxol)

ESMO-ESGO-ESTRO Consensus Conference on Endometrial Cancer: Diagnosis, Treatment and Follow-up

Nicoletta Colombo, Carien Creutzberg, Frederic Amant, Tjalling Bosse, Antonio González-Martín, Jonathan Ledermann, Christian Marth, Remi Nout, Denis Querleu, Mansoor Raza Mirza, Cristiana SessaInt J Gynecol Cancer. 2016 Jan; 26(1): 2–30. Published online 2015 Nov 12. doi: 10.1097/IGC.0000000000000609

Cisplatin Chemoradiotherapy vs Radiotherapy in FIGO Stage IIIB Squamous Cell Carcinoma of the Uterine Cervix: A Randomized Clinical Trial.

Shrivastava S, Mahantshetty U, Engineer R, Chopra S, Hawaldar R, Hande V, Kerkar RA, Maheshwari A, Shylasree TS, Ghosh J, Bajpai J, Gurram L, Gulia S, Gupta S; Gynecologic Disease Management Group. JAMA Oncol. 2018 Apr 1;4(4):506-513. doi: 10.1001/jamaoncol.2017.5179.PMID: 29423520 Free PMC Article

National Cancer Control Programme in India: Proposal for Organization of Chemotherapy and Systemic Therapy Services

Seema Gulia, Manju Sengar, Rajendra Badwe, Sudeep GuptaJ Glob Oncol. 2017 Jun; 3(3): 271–274. Published online 2016 Jun 22. doi: 10.1200/JGO.2015.001818PMCID: PMC5493213ArticlePubReaderPDF–458KCitation

National Cancer Contraol Program

European society of medical oncology (ESMO) 2019 meeting report features practice changing data in gynecologic malignancies. Herzog TJ, Secord AA, Coleman RL, Naumann RW. Gynecol Oncol. 2020 Feb;156(2):265-270. doi: 10.1016/j.ygyno.2019.11.010. Epub 2020 Jan 3.PMID: 31911006

Immune checkpoint expression, microsatellite instability, and mutational burden: Identifying immune biomarker phenotypes in uterine cancer.

Jones NL, Xiu J, Rocconi RP, Herzog TJ, Winer IS.

Gynecol Oncol. 2020 Feb;156(2):393-399. doi: 10.1016/j.ygyno.2019.11.035. Epub 2019 Dec 24.PMID: 31882243

Ovarian Cancer – Dr. Sudeep Gupta

The search continues: Looking for predictive biomarkers for response to mTOR inhibition in endometrial cancer

Larissa A. Meyer, Brian M. Slomovitz, Bojana Djordjevic, Shannon N. Westin, David A. Iglesias, Mark F. Munsell, Yunyun Jiang, Rosemarie Schmandt, Russell R. Broaddus, Robert L. Coleman, John M. Galbincea, Karen H. LuInt J Gynecol Cancer. Author manuscript; available in PMC 2015 May 1.Published in final edited form as: Int J Gynecol Cancer. 2014 May; 24(4): 713–717. doi: 10.1097/IGC.0000000000000118PMCID: PMC4039301ArticlePubReaderPDF–229KCitation

Acute hematological toxicity during post-operative bowel sparing image-guided intensity modulated radiation with concurrent cisplatin.

Lewis S, Chopra S, Naga P, Pant S, Dandpani E, Bharadwaj N, Mahantshetty U, Engineer R, Swamidas J, Ghosh J, Gupta S, Shrivastava S. Br J Radiol. 2018 Dec;91(1092):20180005. doi: 10.1259/bjr.20180005. Epub 2018 Oct 3.PMID: 30179056 Free PMC Article

Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer

Daniela Matei, Virginia Filiaci, Marcus E. Randall, David Mutch, Margaret M. Steinhoff, Paul A. DiSilvestro, Katherine M. Moxley, Yong M. Kim, Matthew A. Powell, David M. O’Malley, Nick M. Spirtos, William Small, Jr., Krishnansu S. Tewari, William E. Richards, John Nakayama, Ursula A. Matulonis, Helen Q. Huang, David S. MillerN Engl J Med. Author manuscript; available in PMC 2020 Jan 8.Published in final edited form as: N Engl J Med. 2019 Jun 13; 380(24): 2317–2326. doi: 10.1056/NEJMoa1813181PMCID: PMC6948006ArticlePubReaderPDF–559KCitation

Autophagy Machinery as a Promising Therapeutic Target in Endometrial Cancer

Stephanie I. Nuñez-Olvera, Dolores Gallardo-Rincón, Jonathan Puente-Rivera, Yarely M. Salinas-Vera, Laurence A. Marchat, Raúl Morales-Villegas, César López-CamarilloFront Oncol. 2019; 9: 1326. Published online 2019 Nov 29. doi: 10.3389/fonc.2019.01326PMCID: PMC6896250

Carboplatin and Taxol

Chemotherapy for Endometrial Cancer in Adjuvant and Advanced Disease Settings

Christine M. Bestvina, Gini F. FlemingOncologist. 2016 Oct; 21(10): 1250–1259. Published online 2016 Jul 13. doi: 10.1634/theoncologist.2016-0062PMCID: PMC5061541

cisplatin
Chemotherapy and chemoradiotherapy

Phase III Trial: Adjuvant Pelvic Radiation Therapy Versus Vaginal Brachytherapy Plus Paclitaxel/Carboplatin in High-Intermediate and High-Risk Early-Stage Endometrial Cancer

Marcus E. Randall, Virginia Filiaci, D. Scott McMeekin, Vivian von Gruenigen, Helen Huang, Catheryn M. Yashar, Robert S. Mannel, Jae-Weon Kim, Ritu Salani, Paul A. DiSilvestro, James J. Burke, Thomas Rutherford, Nick M. Spirtos, Keith Terada, Penny R. Anderson, Wendy R. Brewster, William Small, Carol A. Aghajanian, David S. MillerJ Clin Oncol. 2019 Jul 20; 37(21): 1810–1818. Published online 2019 Apr 17. doi: 10.1200/JCO.18.01575PMCID: PMC6804858ArticlePubReaderPDF–937KCitation

Hormone replacement therapy for women previously treated for endometrial cancer

Katharine A Edey, Stuart Rundle, Martha HickeyCochrane Database Syst Rev. 2018 May; 2018(5): CD008830. Published online 2018 May 15. doi: 10.1002/14651858.CD008830.pub3PMCID: PMC6494585

Thrombocytopenia ~ Carboplatin

Reversal of obesity-driven aggressiveness of endometrial cancer by metformin

Hui Guo, Weimin Kong, Lu Zhang, Jianjun Han, Leslie H Clark, Yajie Yin, Ziwei Fang, Wenchuan Sun, Jiandong Wang, Timothy P Gilliam, Douglas Lee, Liza Makowski, Chunxiao Zhou, Victoria L Bae-JumpAm J Cancer Res. 2019; 9(10): 2170–2193. Published online 2019 Oct 1. PMCID: PMC6834476

Neoadjuvant chemotherapy followed by surgery for advanced-stage endometrial cancerN.

M. de Lange, N.P.M. Ezendam, J.S. Kwon, I. Vandenput, D. Mirchandani, F. Amant, L.J.M. van der Putten, J.M.A. PijnenborgCurr Oncol. 2019 Apr; 26(2): e226–e232. Published online 2019 Apr 1. doi: 10.3747/co.26.4655PMCID: PMC6476439ArticlePubReaderPDF–485KCitation

Value of combined adjuvant chemotherapy and radiation on survival for stage III uterine cancer: is less radiation equal to more?

Chiachien Jake Wang, Alana Christie, Michael R. Folkert, Xian-Jin Xie, Kevin AlbuquerqueJ Gynecol Oncol. 2018 Jul; 29(4): e49. Published online 2018 Mar 6. doi: 10.3802/jgo.2018.29.e49PMCID: PMC5981101ArticlePubReaderPDF–1.0MCitation

Immunotherapy in endometrial cancer: new scenarios on the horizon

Chiara Di Tucci, Carmela Capone, Giulia Galati, Valentina Iacobelli, Michele C Schiavi, Violante Di Donato, Ludovico Muzii, Pierluigi Benedetti PaniciJ Gynecol Oncol. 2019 May; 30(3): e46. Published online 2019 Jan 8. doi: 10.3802/jgo.2019.30.e46PMCID: PMC6424849ArticlePubReaderPDF–4.0MCitation

Imaging in endometrial carcinoma Silvana C Faria, Tara Sagebiel, Aparna Balachandran, Catherine Devine, Chandana Lal, Priya R BhosaleIndian J Radiol Imaging. 2015 Apr-Jun; 25(2): 137–147. doi: 10.4103/0971-3026.155857PMCID: PMC4419423

Chemotherapeutic Agents – General video

New therapies for advanced, recurrent, and metastatic endometrial cancersVicky Makker, Angela K. Green, Robert M. Wenham, David Mutch, Brittany Davidson, David Scott MillerGynecol Oncol Res Pract. 2017; 4: 19. Published online 2017 Dec 2. doi: 10.1186/s40661-017-0056-7PMCID: PMC5712183

Advances in Gynaecological Cancers Management

The Global Cancer Genomics Consortium’s Second Annual Symposium: Genomics Medicine in Cancer ResearchRakesh Kumar, Anelia Horvath, Raja Mazumder, Masakazu Toi, Fumiaki Sato, M. Radhakrishna Pillai, Luis Costa, Maria Carmo-Fonseca, Stefan Knapp, Amit Dutt, Sudeep Gupta, Rajendra BadweGenes Cancer. 2013 May; 4(5-6): 196–200. doi: 10.1177/1947601913484582PMCID: PMC3782003ArticlePubReaderPDF–161KCitation

Adjuvant chemotherapy in locally advanced cervical cancer: the ceiling remains unbrokenSudeep GuptaJ Gynecol Oncol. 2019 Jul; 30(4): e97. Published online 2019 May 22. doi: 10.3802/jgo.2019.30.e97PMCID: PMC6543111ArticlePubReaderPDF–812KCitation

Modeling Endometrial Cancer: Past, Present, and FutureTom Van Nyen, Cristian P. Moiola, Eva Colas, Daniela Annibali, Frédéric AmantInt J Mol Sci. 2018 Aug; 19(8): 2348. Published online 2018 Aug 9. doi: 10.3390/ijms19082348PMCID: PMC6121384

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